| Citation | Discoveries of renal, endocrine and brain mechanisms of electrolyte homeostasis. Elucidation of chemical, hormonal and sensory determinants of genesis and satiation of genetically programmed ingestive behaviour; that sodium appetite is specific, innate, commensurate with body deficit in several species is, determined by extracellular brain [Na] and angiotensin, and that both [Na] sensors and osmoreceptors subserve thirst. The specific hormonal basis of sodium appetite in stress and reproduction. First formal demonstration of Na deficiency in wild animals and the basis of evolution of capacity of wild and pastoral ruminants to adapt to large Na deficient areas of the planet.
The mode of renal regulation during disproportionate electrolyte subtraction from the body, the idea of cervical skin loop adrenal autotransplantation giving access to blood supply in the conscious animal, (giving basic knowledge of control of aldosterone secretion). The role of excess salt in hypertension including chimpanzee studies. |