| Citation | Cantrell is known internationally for her insightful delineation of the molecular cell biological basis of T lymphocyte development and activation, which are key to the comprehension and manipulation of immune responses. Her seminal contributions include identifying key roles for the Ras family GTPases, demonstrating that the cellular location and kinetics of production of signalling lipids are crucial determinants of lymphocyte activation as well as unravelling the downstream serine kinase pathways which ultimately control T-lymphocyte function. She is noted for her multidisciplinary approach and the enlightened combination of biochemical, cell biological, transgenic and gene knock-out technologies. |