| Citation | Phillip Sharp has made fundamental contributions to cancer biology and to understanding gene structure and regulation. His seminal discovery of 'split genes' in eukaryotic cells and the associated mechanism of pre mRNA splicing resulted in numerous awards and honours, including the Nobel Prize in Physiology or Medicine (1993), the Lasker Prize (1988) and the General Motors Prize for Cancer Research (1986). He developed basic laboratory techniques used by a generation of molecular biologists, was a co founder of major biotechnology companies and a pioneer of commercial applications for recombinant DNA technology. He is also a prominent US science adviser. |