Reference numberPP/20/8
Previous numbersPP/52/8
TitlePrinted proof, 'On the estimation of uric acid in urine: a new process by means of saturation with ammonium chloride' by Frederick Gowland Hopkins
DescriptionHopkins writes: 'The process to be described depends upon the following facts:— 1. Ammonium urate is wholly insoluble in saturated solutions of ammonium chloride. 2. If solutions, such as urine, which contain the mixed urates of different bases be saturated with ammonium chloride, the large mass-influence of the latter ensures the rapid and complete conversion of all the uric acid into biurate of ammonium, which, in accordance with (1), is, pari passu, thrown out of solution. In the case of urine, saturation with ammonium chloride is followed by a complete precipitation of the uric acid present in the course of two hours at most.'

Annotations in pencil and ink.

Subject: Biology / Chemistry

Received 30 May 1892. Read 16 June 1891. Communicated by Philip Henry Pye-Smith.

A version of this paper was published in volume 52 of the Proceedings of the Royal Society as 'On the estimation of uric acid in urine: a new process by means of saturation with ammonium chloride'.
Physical descriptionInk and graphite pencil on paper
Digital imagesView item on Science in the Making
Access statusOpen
Related materialDOI: 10.1098/rspl.1892.0055
Fellows associated with this archive
NA6168Hopkins; Sir; Frederick Gowland (1861 - 1947)1861 - 1947
NA8016Pye-Smith; Philip Henry (1839 - 1914)1839 - 1914
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