|Title||Printed proof, 'On the estimation of uric acid in urine: a new process by means of saturation with ammonium chloride' by Frederick Gowland Hopkins|
|Description||Hopkins writes: 'The process to be described depends upon the following facts:— 1. Ammonium urate is wholly insoluble in saturated solutions of ammonium chloride. 2. If solutions, such as urine, which contain the mixed urates of different bases be saturated with ammonium chloride, the large mass-influence of the latter ensures the rapid and complete conversion of all the uric acid into biurate of ammonium, which, in accordance with (1), is, pari passu, thrown out of solution. In the case of urine, saturation with ammonium chloride is followed by a complete precipitation of the uric acid present in the course of two hours at most.'|
Annotations in pencil and ink.
Subject: Biology / Chemistry
Received 30 May 1892. Read 16 June 1891. Communicated by Philip Henry Pye-Smith.
A version of this paper was published in volume 52 of the Proceedings of the Royal Society as 'On the estimation of uric acid in urine: a new process by means of saturation with ammonium chloride'.
|Physical description||Ink and graphite pencil on paper|
|Digital images||View item on Science in the Making|
|Related material||DOI: 10.1098/rspl.1892.0055|
Fellows associated with this archive
|NA6168||Hopkins; Sir; Frederick Gowland (1861 - 1947)||1861 - 1947|
|NA8016||Pye-Smith; Philip Henry (1839 - 1914)||1839 - 1914|