Paper, 'An account of the appearance of the matter of the small pox seen thro' a microscope' by J T [John Theophilus] Desaguliers Desaguliers writes: 'Having a daughter of a year old sick of the distinct small pox and pretty full of pustules I was desirous to have my eldest son [John Theophilus Jr (1718-1751)], who is between 4 and 5 years old, inoculated with the matter taken from his sister'. He explains that he had a surgeon infect his son with the smallpox virus, and shares his observations of smallpox under the microscope. Includes two diagrams of Desaguliers' observations from the microscope. Subject: Pathology Read to the Royal Society on 23 June 1723 13 June 1723