Laboratory notebook of John Henry Gaddum Experimental notes, relating to depressor substances. The volume has been used and then turned upside down and continued from other side. Experiments include assays with eserine on a cat (p3), the destructive action of dried blood on acetylcholine (p7), extracts from a dog's alimentary canal (p11), stimulation of nerves to dog's intestine under ether (p13), extracts tested on a rabbit's intestine and a cat's gastrocnemius (p15, 31), assays of acetylcholine on a frog's rectus (pp17-23), extracts of horse suprarenal and sympathetic system (pp36-37), tests of these extracts on a frog rectus, tests of destructive action of dried blood on a rabbit's intestine, extracts from horse spleen (p41), extracts from a dog intestine (p45), test of extracts on a rabbit's blood pressure (p49-57), tests by collusion (p89-91), tests of rat hyperthyroid, effects of atrophine (p115), test of ouabain on frogs. Many more variations on the extraction from organs, usually followed by testing of extract on a rabbit's or cat's blood pressure, or assays on a frog's rectus. p97: note on 'various unsuccessful attempts to show that sympathetic ganglia act by liberating acetylcholine.' Contains a two page report on the potency of the standard preparations of strophanthus (between pp56-57). Pencil drawing of dissection of a dog's face (p94). 2 page report from Professor G T Morgan on the Toxicity of Sodium Phenanthridine-9-Carboxylate (between pp94-95). Ballot from the semi-annual meeting of the Physiological Society (p167). Contains loose sheets with data (between cover and first/last pages). August 1931-June 1933