Correspondence between Prime Minister's office and Sir John Vane Correspondence with 10 Downing Street covering Sir John Vane's opinions on the Greenfield Report which related to the effective prescribing of drugs, a letter raising concerns about cuts in academic funding and a letter relating to experimentation on animals. The file includes replies from Margaret Thatcher, Prime Minister. Also in the file is a letter congratulating Margaret Thatcher on her election to the Royal Society as a fellow elected under statute 12 in 1983 and her reply to Sir John Vane. 25 March 1983 - 8 July 1985