Paper, 'Note on the knee-jerk and the correlation of action of antagonistic muscles' by Charles Scott Sherrington Sherrington writes: 'The muscular reaction known as the knee-jerk is notoriously affected by conditions obtaining in w hat is often described as a reflex arc, consisting of afferent and efferent paths, and a centre situate in the lumbar portion of the spinal cord. I recently described experi­ments determining more particularly than hitherto the locality of the muscular and nervous mechanism on which the jerk depends.' Annotations in pencil and ink. Subject: Physiology Received 1 February 1893. Read 9 February 1893. Communicated by Michael Foster. A version of this paper was published in volume 52 of the Proceedings of the Royal Society as 'Note on the knee-jerk and the correlation of action of antagonistic muscles'. 1893