Person Brenner; Sydney (1927 - 2019) Brenner Sydney 1927 - 2019 British Male Germiston, South Africa 13/01/1927 19270113 05/04/2019 20190405

Molecular Biologist Career: Distinguished Research Professor, Salk Institute for Biological Studies Medals and prizes: Nobel Prize (Physiology or Medicine) 2002 Honours: CH 1987 Sydney Brenner was a Nobel Prize-winning biologist who made many seminal contributions to molecular biology. Joining the field at its inception in the 1950s, Sydney worked with notable contemporaries on studies of Escherichia coli and the viruses that attack this bacterium to reveal much about the structure and function of the genetic code and, in particular, RNA. He proposed the existence of messenger RNA as an intermediary between DNA and protein. Sydney subsequently revealed that triplets of nucleotides within RNA encode the individual amino acids of a protein, as well as signals for stopping protein manufacture. Consequently, he showed that the order of such triplets directly determines the order of amino acids in a protein. Sydney successfully established Caenorhabditis elegans as a model organism, himself using the roundworm to study organ development and apoptosis. For these achievements, he earned the 2002 Nobel Prize in Physiology or Medicine. Well known for providing insightful ideas to fellow scientists, Sydney has founded and led several research institutes and was instrumental in guiding Singapore’s investment in biomedical research. Royal Society roles: Council: 1975-1977 Medals and prizes: Royal Medal 1974; Copley Medal 1991 Lectures: Croonian 1986 Fellow 18/03/1965 38 References: 'Address of the President, Sir Michael Atiyah, Given at the Anniversary Meeting on 29 November 1991' in NR 1992 vol 46 pp 155-169 R Holliday, 'The early years of molecular biology: personal recollections' in NR 2003 vol 57 pp 195-208 R A Crowther, 'Viruses and the development of quantitative biological electron microscopy' in NR 2004 vol 58 pp 65-81 Mariana Cook 'Faces of Science', 2005 p36-7 International Standard Archival Authority Record for Corporate Bodies, Persons and Families - ISAAR(CPF) - Ottawa 1996 ISBN 0-9696035-3-3 National Council on Archives, Rules for the Construction of Personal, Place and Corporate Names, 1997 13 Jan 1927 - 05 April 2019 NA3395 21/11/2001 Andyg pmab 28/03/2023 RS_NET\JonathanB Yes http://viaf.org/viaf/84854329 96faa0be-b88e-40d1-9a4d-6fafe941c484