Person Tata; Jamshed Rustom (1930 - 2020) Tata Jamshed Rustom 1930 - 2020 British Male Mumbai [Bombay], Maharashtra, India, Asia 13/04/1930 19300413 London 08/10/2020 20201008

Endocrinologist Cell biology Developmental biology Physiology Endocrinology Thyroid hormones Amphibian metamorphosis Genetics Career: Postdoctoral fellow, Sloan-Kettering Institute (1954-1956); National Institute for Medical Research (NIMR), London (1956-1960), staff scientist (1962-1973), Head of the Division of Developmental Biochemistry (1973-1996); visiting scientist, University of Stockholm (1960-1962); retired 1996; visiting scientist at NIMR until the site closed in 2016 Medals/Awards: Colworth Medal of the Biochemical Society 1964 Jamshed Tata was an endocrinologist and developmental biologist whose research revealed much about the cellular and molecular actions of thyroid and other hormones. Critical for vital processes during development and in adulthood, Jamshed was the first to show that thyroid hormone has a direct effect on gene expression. Born and educated in Bombay, he began his research career in Paris and changed scientific thinking on how thyroid hormone acts on cells to raise the basal metabolic rate. Although the consensus at the time suggested that thyroid hormone interfered with mitochondrial energy production, Jamshed proved that, in fact, it regulated the activity of genes. Jamshed subsequently began to study metamorphosis in amphibians, a process in which thyroid hormone was known to be involved. Once again, he overturned an earlier theory by showing that as tadpoles develop into frogs, thyroid hormone controls gene expression to stimulate the loss of the tail. In addition, he played a role in demonstrating the multiplicity of RNA polymerase. Dr Jamshed Tata FRS died on 8 October 2020. Committee and panels: Panel III, North American and Australasia (1997-2002); International Networks Committee (2010-2014); Royal Society Research Grant Scheme, Board F (Chair 2005-2007); International Exchanges Committee (2013-2018) Fellow 15/03/1973 42 Sources: Wikipedia https://royalsociety.org/people/jamshed-tata-12388/ [accessed 16 October 2020] International Standard Archival Authority Record for Corporate Bodies, Persons and Families - ISAAR(CPF) - Ottawa 1996 ISBN 0-9696035-3-3 National Council on Archives, Rules for the Construction of Personal, Place and Corporate Names, 1997 13 Apr 1930 - 8 Oct 2020 NA3902 21/11/2001 Andyg Martind 23/03/2026 RS_NET\VirginiaM Yes http://viaf.org/viaf/5095785 92891649-c7d6-40bf-86f4-17a0b9ac4308