| RefNo | EC/1985/34 |
| Previous numbers | Cert XXI, 216 |
| Level | Item |
| Title | Sambrook, Joseph Frank: certificate of election to the Royal Society |
| Date | 1984 |
| Description | Citation typed |
| Citation | Joseph Sambrook has made many important contributions to molecular and biochemical genetics, studying animal viruses, and particularly those viruses with DNA that integrate into the host cell genome. He was a member of the group that first demonstrated the physical integration of the DNA sequences of SV40 and polyoma virus into the chromosomes of the cells they transform. He subsequently defined the sequences which are necessary and sufficient to effect malignant transformation, and was a pioneer in the use of restriction enzymes for the physical mapping of mutations in adenovirus. He was the first to analyse the DNA sequences of the integration sites of SV40, work which confirmed the onionskin model of excision. More recently Sambrook has analysed the expression of influenza virus haemagglutinin from genes cloned in SV40 vectors and has begun to study the factors influencing the transport of haemagglutinin to the cell surface by in vitro modification of the genes. |
| AccessStatus | Closed |
Fellows associated with this archive
| Code | PersonName | Dates |
| NA4781 | Sambrook; Joseph Frank (1939 - 2019) | 1939 - 2019 |