| RefNo | EC/1972/29 |
| Previous numbers | Cert XIX, 66 |
| Level | Item |
| Title | Sanger, Ruth Ann: certificate of election to the Royal Society |
| Description | Citation typed |
| Citation | Distinguished for the important part she has played in investigations that have enlarged knowledge of all the well-established human red cell antigens. Outstanding contributions have been her recognition and analysis of the genetically important Rh gene complex -D-. She discovered that the antigens Tj-a and P-k belong to the P system (which until then was thought a simple one), and ideas about it, consequently had to be completely changed. Her recognition that an antigen, S, belonged to the MN system revolutionized understanding of that system also, and her observation that people lacking the antigen U also lacked S and s afforded further insight into its complexity. Ruth Sanger was the first to perceive that the antigen called X-g-a was X-linked. The identification of this common sex-linked character in man precipitated investigation in many parts of the world, and in this field she remains the central figure. Her work is largely responsible for the emergence of a map of genes located on the X-chromosome and for new insight into chromosomal mechanisms behind abnormalities of sex, such as those described by Turner and by Klinefelter. |
| AccessStatus | Open |
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Fellows associated with this archive
| Code | PersonName | Dates |
| NA7043 | Sanger; Ruth Ann (1918 - 2001); immunogeneticist and serologist | 1918 - 2001 |