| Citation | Distinguished for his many contributions to neurobiology, especially for his elegant analysis of central nervous function in the leech. In an early series of papers (jointly with Kuffler), Nicholls provided a highly original electrophysical account of glial cells and demonstrated the importance of extracellular potassium as a signal within the nervous system. Later papers have focussed on the detailed properties of identified neurones in the leech central nervous system, studying the connexions and the function role of neurone in the animal and at the same time answering questions of fundamental importance to neurobiology. This is particularly well shown in his recent work on regeneration in the leech central nervous system where electrophysiological, anatomical and tissue culture techniques are combined most impressively. |