| RefNo | EC/1992/30 |
| Level | Item |
| Title | Ramage, Robert: certificate of election to the Royal Society |
| Date | 1985 |
| Description | Citation typed |
| Citation | Distinguished for his versatile and innovative contributions to a number of important areas of organic chemistry. His seminal ideas on sesquiterpene biosynthesis were followed by stereochemically controlled chiral syntheses of a range of complex terpenes. He participated with R.B. Woodward in the classical synthesis of cephalosporin C, a feat which significantly influenced later synthetic approaches to the beta-lactam antibiotics. Together with A.R. Battersby he solved the enigma of colchicine biosynthesis, established the structure of a new series of alkaloids and determined the biosynthetic pathway to these homoaporphines. In the ergot alkaloid field he has designed a new synthesis of lysergic acid. Initially with G.W. Kenner and then independently he has made very extensive contributions to polypeptide chemistry particularly in the gastrin field with structural elucidations followed by total synthesis of mini-gastrin and porcine big gastrin. He has innovated many useful methodologies for peptide synthesis and applied them successfully to high molecular weight polypeptides. He has developed the use of dioxalanone derivatives as versatile synthetic precursors and has employed them in elegant syntheses of naturally occurring tetronic acids and the highly labile biosynthetic precursor prephenic acid. |
| AccessStatus | Closed |
Fellows associated with this archive
| Code | PersonName | Dates |
| NA4097 | Ramage; Robert (1935 - 2019) | 1935 - 2019 |