Citation | Professor Peters is an outstanding clinical research worker who has made seminal contributions to understanding the pathogenesis of glomerulonephritis. He and his group delineated the role of coagulation factors and of complement in glomerular injury and were the first to use in vivo complement turn-over exclusively for this purpose. They characterised the 'nephritic factor' as an autoantibody and showed it to predispose to rather than to result from nephritis. They demonstrated the therapeutic value of immunosuppression in nephritis and pioneered the use of plasma exchange for this and other antibody-mediated diseases. More recently Professor Peters has investigated the handling of immune complexes and was the first to demonstrate that the classical complement pathway prevented immune precipitation. In addition to his own research contributions, Professor Peters plays a dominant role in promoting high quality clinical research in the United Kingdom. As Professor of Medicine at the Royal Postgraduate Medical School he built up a multidisciplinary department of the highest academic standards - and is now doing the same at Cambridge. |