| Citation | Yvonne Jones is distinguished for fundamental biological insights from studies on the structural biology of cell surface recognition and signalling. The early structure of TNF was a landmark result for a system of great biomedical importance. Jones also pioneered the analysis of type 1 membrane proteins, from the first cell adhesion molecule, CD2, which defined the current paradigm for adhesive protein-protein interactions, to cell surface signalling assemblies central to cellular immunology and developmental biology. This body of work, built upon strong links with clinically related groups, has had a major impact on our understanding of molecular mechanisms in cellular communication. |