Citation | Ken Wolfe is a pioneer of the field of genome evolution. His work has had profound impact on our understanding of eukaryotic genomes, particularly in regard to gene duplication and the relationship between a gene’s location and its function. Although he has worked on many different organisms during his career, his research has always focused on the central questions of how eukaryotic genomes are organized, and how that organization evolved. He is best known for his discovery in 1997 of the yeast whole-genome duplication (WGD), a phenomenon that reshaped our understanding of yeast biology and eukaryotic genome evolution. |