| RefNo | EC/2021/29 |
| Level | Item |
| Title | Marshall, Fiona Hamilton: certificate of election to the Royal Society |
| Date | 21 April 2021 |
| Description | Certificate endorsing election of Fiona Marshall as a Fellow of the Royal Society. Includes personal details of the elected Fellow, citation giving the reasons for election, and names of proposers. Signed by the Executive Director of the Royal Society, Julie Maxton. |
| Citation | Fiona Marshall is known for her discoveries in the field of G protein-coupled receptors (GPCRs). Her early work included cloning of the GABAB receptor, providing demonstration that GPCRs may function in multiprotein complexes, and the cloning of two families of receptors activated by cellular and microbial metabolites. Together with her scientific team at Heptares, she solved de novo X-ray structures of numerous GPCRs revealing multiple unexpected allosteric binding sites. These structures have enabled structure-based drug design leading to a pipeline of drugs in clinical development for diseases including Alzheimer's disease and cancer. Her work is an impressive example of how basic academic science can be translated into healthcare benefits and commercial success. |
| Extent | 4p |
| Format | Computer printout |
| PhysicalDescription | A4 papers |
| AccessStatus | Closed |
| AccessConditions | Election certificates are subject to 50 year closure period from date of election. Details of proposers and date certificate was first submitted for candidacy are kept confidential until the 50 year closure period has elapsed. |