| RefNo | EC/2024/15 |
| Level | Item |
| Title | Carter, Andrew Philip: certificate of election to the Royal Society |
| Date | 21 April 2024 |
| Description | Certificate endorsing election of Andrew Carter as a Fellow of the Royal Society. Includes personal details of the elected Fellow, citation giving the reasons for election, and names of proposers. Signed by the Executive Director of the Royal Society, Julie Maxton. |
| Citation | Andrew Carter is distinguished for his fundamental contributions to understanding the structure and mechanism of cytoplasmic dynein, a complex molecular motor that transports cargoes within the cell. His work combined protein crystallography, electron microscopy and single-molecule biophysics with new methods developments to explain how dynein uses the energy of ATP hydrolysis to move along microtubules. Andrew elucidated the molecular basis by which the large dynactin cofactor interacts with dynein and stimulates its activity. He discovered that adaptor proteins, responsible for selecting specific cargoes, directly regulate long-range transport and revealed the structural basis for their interaction with the dynein-dynactin complex. Recently, by determining a structure of an axonemal dynein, which powers the beating of cilia, he discovered a novel regulatory factor he termed Shulin, that is required for dynein delivery to growing cilia. |
| Extent | 4p |
| Format | Computer printout |
| PhysicalDescription | A4 papers |
| AccessStatus | Closed |
| AccessConditions | Election certificates are subject to 50 year closure period from date of election. Details of proposers and date certificate was first submitted for candidacy are kept confidential until the 50 year closure period has elapsed. |