| RefNo | EC/2024/16 |
| Level | Item |
| Title | Chinnery, Patrick Francis: certificate of election to the Royal Society |
| Date | 21 April 2024 |
| Description | Certificate endorsing election of Patrick Chinnery as a Fellow of the Royal Society. Includes personal details of the elected Fellow, citation giving the reasons for election, and names of proposers. Signed by the Executive Director of the Royal Society, Julie Maxton. |
| Citation | Patrick Chinnery has advanced our understanding of how mitochondrial diseases originate, is inherited and expressed. He showed that a reduction in mitochondrial DNA (mtDNA) content within primordial germ cells leads to major changes in mutation load over one generation. This explains how mutations spread rapidly throughout the population and cause diseases of differing severity. He showed that most humans harbour different mixtures of mtDNA molecules which provides a reservoir for population genetic diversity which is modulated by the cell nucleus during maternal transmission, and that there is ongoing transfer of mtDNA into the cell nucleus shaping genome evolution. |
| Extent | 4p |
| Format | Computer printout |
| PhysicalDescription | A4 papers |
| AccessStatus | Closed |
| AccessConditions | Election certificates are subject to 50 year closure period from date of election. Details of proposers and date certificate was first submitted for candidacy are kept confidential until the 50 year closure period has elapsed. |