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Authorised form of nameWilkie; Douglas Robert (1922 - 1998); physiologist
Dates1922 - 1998
NationalityBritish
Place of birthLondon, England, United Kingdom
Date of birth02 October 1922
Place of deathLondon, England, United Kingdom
Date of death21 May 1998
DatesAndPlacesBurial: Highgate Cemetery, Highgate, North London, England, United Kingdom.
OccupationPhysiologist
Research fieldMuscle mechanics
Physiology
ActivityEducation:
Bec School and Brighton Technical College; MD Yale (1943) MB BS Lond (1944)
Career:
House physician, University College Hospital, London (1944); assistant lecturer at the Physiology Department, University College London (1945); military service at the Institute of Aviation Medicine in Farnborough (1948-1950); Locke Research Fellow, University College London (1951-54); Reader in Experimental Physiology (1954-65); Professor of Experimental Physiology (1965-69); Jodrell Professor and Head of Physiology Department; (1969-79) (Emeritus); Jodrell Research Professor of Physiology, London University 1979-88 (Emeritus); retired (1988).
Memberships:
MRCP 1945
FRCP 1972
Membership categoryFellow
Date of election18/03/1971
Age at election48
ProposerArchibald Vivian Hill
Alan Lloyd Hodgkin
Andrew Fielding Huxley
Hugh Esmor Huxley
John Carew Eccles
RelationshipsSpouse: (m. 1949) June Hill (d. 1997), medical scientist, (divorced 1982).
Children: Andrew Wilkie, medical scientist.
PublishedWorksRCN 21080
OtherInfoHas made numerous experimental and theoretical contributions to the study of muscle, and his profound and critical understanding of the field has been an important factor in recent progress.
His early work provided the best data available even now on the force-velocity, active-state and series-elastic characteristics of muscle.
His simultaneous measurements of thermal, mechanical and chemical changes in a wide variety of types of contraction have shown that the total energy liberated as work and heat is accounted for by the amount of phosphocreatine hydrolysed. He is the only person able to make all these different types of technically difficult measurements himself and so provide the essential condition for reliable correlations to be made between them. He has greatly clarified the application of thermodynamics to muscle. His new methods for suddenly freezing a muscle is providing data of a quality previously unattainable concerning the chemical changes during contraction itself.
Royal Society Obituary or MemoirClick to view (may be contained within a meeting notice, presidential address or list of death notices)
Related imagesDiscover a selection of related images in our picture library
SourceObituaries:
Biographical Memoirs of Fellows of the Royal Society 2001 vol 47 pp 481-495, plate, by Roger C Woledge
Virtual International Authority Filehttp://viaf.org/viaf/277488148
CodeNA4874
Archives associated with this Fellow
RefNoTitleDate
DRW/2/2/19Scientific correspondence between Douglas Robert Wilkie and Francis D. Carlson1960-1965
DRW/1/2/2Ice membrane UCL student lists, collected by Douglas Robert Wilkie1957-1958
DRW/1/2/3Lectures to Architecture students, delivered by Douglas Robert Wilkie1961
IM/GA/SGRS/8436Wilkie, Douglas Robert1986
DRW/2/2/1General scientific and professional correspondence file of Douglas Robert Wilkie for the years 1945-19491945-1949
DRW/2/2/3General scientific and professional correspondence file of Douglas Robert Wilkie for the years 1957-19581957-1958
DRW/1/1/3Early research on muscle function, conducted by Douglas Robert Wilkie1940s
IM/GA/JGRS/7859Wilkie, Douglas Robert1976
EC/1971/32Wilkie, Douglas Robert: certificate of election to the Royal Society
DRW/1/1/1Force and Velocity in Human Muscle: Experimental results obtained by Douglas Robert Wilkie1935-1939
DRWCorrespondence and scientific papers of Douglas Robert Wilkie1940s-1990s
DRW/2Correspondence of Douglas Robert Wilkie1940-1990
DRW/1Scientific papers of Douglas Robert Wilkiec. 1940-1990
DRW/1/1Experiments and research papers of Douglas Robert Wilkie1940-1990
DRW/3Personal records of Douglas Robert Wilkie1940-1990
DRW/1/2Teaching material of Douglas Robert Wilkie1953-1976
DRW/1/1/4Physiology notes of Douglas Robert Wilkie1941
DRW/1/1/5Original records, notes, and letters, produced by Douglas Robert Wilkie1945-1948
DRW/1/1/2Experiment notes made by Douglas Robert Wilkie, at Brighton Technical College Physics Department1939-1940
DRW/1/1/6Resistance Computer Circuit subject file assembled by Douglas Robert Wilkie1946-1947
DRW/1/1/7Pre-publication records of papers on human muscle function, organised by Douglas Robert Wilkie1948-1950
DRW/1/1/8Medical and hygiene field notes of Douglas Robert Wilkie1948
DRW/1/1/9Old research: Effects of Marching in Flying Boots and Golden ratio preprint, collated by Douglas Robert Wilkie1949
DRW/1/1/10File titled 'Statistics: Area Problem 1', arranged by Douglas Robert Wilkie1950-1951
DRW/1/1/11Patent records assembled by Douglas Robet Wilkie1950s
DRW/1/1/12File on Compression: high pressure physiological equipment, arranged by Douglas Robert Wilkie1950-1951
DRW/1/1/13Miscellaneous research notes collated by Douglas Robert Wilkie1950s
DRW/1/1/14Book reviews by Douglas Robert Wilkie1950-1960
DRW/1/1/20Junior medical practical physiology experiments undertaken by Douglas Robert Wilkie1957-1958
DRW/1/1/15Experimental work notebook of Douglas Robert Wilkie1951-1952
DRW/1/1/17Experimental Results 1954-1968, obtained by Douglas Robert Wilkie1954-1968
DRW/1/1/16File titled 'Rubber Experiments', organised by Douglas Robert Wilkie1951-1987
DRW/1/1/18Experimental notes, made by Douglas Robert Wilkie1955-1957
DRW/1/1/19Acetylcholine experiments carried out by Douglas Robert Wilkie1956
DRW/1/1/21Research file on "Human power production", assembled by Douglas Robert Wilkie1957-1958
DRW/1/1/22Ice experiments conducted by Douglas Robert Wilkie1957
DRW/1/1/23Muscle heat experiments carried out by Douglas Robert Wilkie1957-1958
DRW/1/1/24Muscle microscopic observations made by Douglas Robert Wilkie1957
DRW/1/1/25Thermopile Corrections investigated by Douglas Robert Wilkie1957-1960
DRW/1/1/26Adenosine Triphosphate Experiments conducted by Douglas Robert Wilkie1957
DRW/1/1/27Scientific Memorabilia collected by Douglas Robert Wilkie1957-1999
DRW/1/1/28File on 'Microelectrodes', assembled by Douglas Robert Wilkie1958-1961
DRW/1/1/29Miscellaneous Research filed by Douglas Robert Wilkie1959-1970
DRW/1/1/30Thermoelasticity experiments conducted by Douglas Robert Wilkie1959
DRW/1/1/31Work on tortoise muscle carried out by Douglas Robert Wilkie1960
DRW/1/1/32File on Ion Membranes, arranged by Douglas Robert Wilkie1960
DRW/1/1/33File on Poikilothermy, organised by Douglas Robert Wilkie1960
DRW/1/1/34File on the Tinsley Glavanometer, assembled by Douglas Robert Wilkie1960
DRW/1/1/35File on Lever Vibrations, arranged by Douglas Robert Wilkie1960
DRW/1/1/36Experiment notes on 'Oscillations equivalent circuit', created by Douglas Robert Wilkie1960-1961
DRW/1/1/37File on 'Oscillations in muscle', compiled by Douglas Robert Wilkie1960-1961
DRW/1/1/38Research Notebook of Douglas Robert Wilkie1961-1973
DRW/1/1/39Myothermic experiments, conducted by Douglas Robert Wilkie1961
DRW/1/1/40Optics file, arranged by Douglas Robert Wilkie1961
DRW/1/1/41File on resistance thermometry and myothermic methods, arranged by Douglas Robert Wilkie1961
DRW/1/1/42Notes on 'Hydraulics of fluid flow in pipes', created by Douglas Robert Wilkie1961
DRW/1/1/43Results of heat experiments (myothermic) on muscle, conducted by Douglas Robert Wilkie1961-1962
DRW/1/1/44Records of myothermic experiments on toads, performed by Douglas Robert Wilkie1962
DRW/1/1/45File on wafer thermopiles, created by Douglas Robert Wilkie1962
DRW/1/1/46Wafer thermopile results obtained by Douglas Robert Wilkie1963-1964
DRW/1/1/47File on the BBC Human Muscle programme, starring Douglas Robert Wilkie1962
DRW/1/1/48Heat measurements taken by Douglas Robert Wilkie1964
DRW/1/1/49Notes on the Fenn effect at various temperatures by Douglas Robert Wilkie1965
DRW/1/1/50Investigation into regression by Douglas Robert Wilkie1965
DRW/1/1/51Experiments on weight and water content conducted by Douglas Robert Wilkie1966
DRW/1/1/52Notes on heart calorimeter experiments, taken by Douglas Robert Wilkie1966
DRW/1/1/53Notes on the Donnan equilibrium, made by Douglas Robert Wilkie1966
DRW/1/1/54Miscellaneous research statistics, collated by Douglas Robert Wilkie1966
DRW/1/1/55Refereeing work of Douglas Robert Wilkie1966-1967
DRW/1/1/56Records of the Biophysical Society Winter Meeting, arranged by Douglas Robert Wilkie1967
DRW/1/1/57Notes on cooling bubbles, taken by Douglas Robert Wilkie1967
DRW/1/1/58Scientific notebook of Douglas Robert Wilkie1967
DRW/1/1/59Golf Society of Great Britain file, arranged by Douglas Robert Wilkie1968
DRW/1/1/60Notebook of scientific experiments, conducted by Douglas Robert Wilkie1968
DRW/1/1/61Notes on the theory of thermoelasticity, created by Douglas Robert Wilkie1969
DRW/1/2/7Lecture on 'The energy balance during muscle contraction', delivered by Wilkie and others1969
DRW/1/1/62File on the rapid freezing of tissue, created by Douglas Robert Wilkie1969
DRW/1/1/63File on the analysis of variance, organised by Douglas Robert Wilkie1969
DRW/1/1/64File on the 1970 Gordon Research Conference on Heart Muscle, attended by Douglas Robert Wilkie1969-1970
DRW/1/1/65File of criticism of Wilkie's ideas on biological energetics by Dr. Barbara E. C. Banks, arranged by Douglas Robert Wilkie1969-1972
DRW/1/1/66Notebook of experiments tackling current physiological problems, created by Douglas Robert Wilkie1970
DRW/1/1/67Notebook of experimental investigations, executed by Douglas Robert Wilkie1970
DRW/1/1/68Notes on breakdown during relaxation, created by Douglas Robert Wilkie1971
DRW/1/1/69File on APG statistics, compiled by Douglas Robert Wilkie1972
DRW/1/1/70File on freezing point apparatus, arranged by Douglas Robert Wilkie1972
DRW/1/1/71File on the analysis of work vs DPL experiments, created by Douglas Robert Wilkie1972
DRW/1/1/72Notebook of experimental notes, made by Douglas Robert Wilkie1972
DRW/1/1/73Notebook of scientific notes, created by Douglas Robert Wilkie1971-1972
DRW/1/1/74Draft of Thermodynamics Book, authored by Douglas Robert Wilkie1972
DRW/1/1/75File on Man Powered Flight, assembled y Douglas Robert Wilkie1970-1979
DRW/1/1/76Research notes on filament theory, assembled by Douglas Robert Wilkie1973-1975
DRW/1/1/77Notebook of lectures and meetings, created by Douglas Robert Wilkie1974
DRW/1/1/78File on chemical nomenclature, created by Douglas Robert Wilkie1975
DRW/1/1/79File on NMR data processing, arranged by Douglas Robert Wilkie1976
DRW/1/1/80File on equations and derivations for a Nature paper, by Douglas Robert Wilkie1977-1978
DRW/1/1/81Notes on heat measurement, taken by Douglas Robert Wilkie1979-1980
DRW/1/1/82File on Creatine Kinase Kinetics, arranged by Douglas Robert Wilkie1979-1990
DRW/1/1/83Notes on electrodes, created by Douglas Robert Wilkie1981
DRW/1/1/84File of reports to the Science and Engineering Research Council, produced by Douglas Robert Wilkie1979-1983
DRW/1/1/85Meeting notes made by Douglas Robert Wilkie1985
DRW/1/1/86Abstracts of papers, arranged by Douglas Robert Wilkie1986-1987
DRW/1/1/87File on an unpublished letter to Nature, arranged by Douglas Robert Wilkie1987-1988
DRW/1/1/88File on the mouse trap, created by Douglas Robert Wilkie1988
DRW/1/1/89File on the statistical theory of chromatography, assembed by Douglas Robert Wilkie1989
DRW/1/1/90File on FRS candidature refereeing, arranged by Douglas Robert Wilkie1988
DRW/1/1/92File on Veech and other brain chemistry, assembled by Douglas Robert Wilkie1988-1990
DRW/1/1/93Notes on lamp resistance, made by Douglas Robert Wilkie1991
DRW/1/1/94Scientific notes made by Douglas Robert Wilkie1986-1997
DRW/1/1/95Notes on dye dilution schedule, assembled by Douglas Robert Wilkiec. 1980s
DRW/1/1/96Notes on the design on the design of float recorder, made by Douglas Robert Wilkiec. 1980s
DRW/1/1/97Notes on Profound hypophosphataemia in patients collapsing after a "fun run", made by Douglas Robert Wilkie1986
DRW/1/1/98Scientific notes on lectures attended, created by Douglas Robert Wilkie1958-1959
DRW/1/2/1Notes on Applied Physiology Lectures, created by Douglas Robert Wilkie1953-1965
DRW/1/2/4File on muscle lecture delivered at Warsaw, by Douglas Robert Wilkie1965
DRW/1/2/8Inaugural lecture delivered by Douglas Robert Wilkie11 February 1970
DRW/1/2/9The Frontiers of Knowledge BBC broadcast, by Douglas Robert Wilkie1970
DRW/1/2/5Lecture on Metabolism, delivered by Douglas Robert Wilkie1967
DRW/1/2/10File of old teaching notes, created by Douglas Robert Wilkiec. 1970s
DRW/1/2/11Lectures on exercise, delivered by Douglas Robert Wilkie1954-1979
DRW/1/2/12Lecture on body temperature, delivered by Douglas Robert Wilkie1974-1976
DRW/1/2/6Lecture on PH and buffers, delivered by Douglas Robert Wilkie1968
DRW/1/2/13File on talks and lectures, delivered by Douglas Robert Wilkie1979-1987
DRW/1/1/99Refereeing work and peer review, carried out by Douglas Robert Wilkie1968-1975
DRW/2/1Subject specific scientific correspondence of Douglas Robert Wilkie1967-1980
DRW/2/2General scientific and professional correspondence of Douglas Robert Wilkie1949-1996
DRW/2/2/18General scientific and professional correspondence of Douglas Robert Wilkie for the years 1990-19961990-1996
DRW/2/3Personal correspondence of and concerning Douglas Robert Wilkie1940-1996
DRW/2/2/17General scientific and professional correspondence file of Douglas Robert Wilkie for the years 1983-19891983-1989
DRW/2/2/4General scientific and professional correspondence file of Douglas Robert Wilkie for the year 1961-19621961-1962
DRW/2/2/5General scientific and professional correspondence file of Douglas Robert Wilkie for the year 19631963
DRW/2/2/6General scientific and professional correspondence file of Douglas Robert Wilkie for the year 19641964
DRW/2/2/7General scientific and professional correspondence file of Douglas Robert Wilkie for the year 19651965
DRW/2/2/8General scientific and professional correspondence file of Douglas Robert Wilkie for the year 19661966
DRW/2/2/9General scientific and professional correspondence file of Douglas Robert Wilkie for the year 19671967
DRW/2/2/10General scientific and professional correspondence file of Douglas Robert Wilkie for the year 19681968
DRW/2/2/16General scientific and professional correspondence file of Douglas Robert Wilkie for the years 1980-19821980-1982
DRW/2/2/11General scientific and professional correspondence file of Douglas Robert Wilkie for the year 19721972
DRW/2/2/12General scientific and professional correspondence file of Douglas Robert Wilkie for the year 19731973
DRW/2/2/13General scientific and professional correspondence file of Douglas Robert Wilkie for the year 19741974
DRW/2/2/15General scientific and professional correspondence file of Douglas Robert Wilkie for the year 19791979
DRW/2/1/1Correspondence file on the arrangements for Einar Lundsgaard Lectures, assembled by Douglas Robert Wilkie1967
DRW/1/1/100File on the Neuroscience Research Program, retained by Douglas Robert Wilkie1964
DRW/2/1/2Letters on gel filtration, arranged by Douglas Robert Wilkie1970-1971
DRW/2/1/3Letters on Freezing PT and buffers, arranged by Douglas Robert Wilkie1971-1972
DRW/2/1/4Correspondence on thermodynamics between Douglas Robert Wilkie and Kenneth George Denbigh1970-1974
DRW/2/1/5Correspondence on thermodynamics between Douglas Robert Wilkie and [Douglas Hugh] Everett1974-1980
DRW/2/1/6Correspondence on thermodynamics between Douglas Robert Wilkie and Herbert Gutfreund1973-1974
DRW/2/1/7Correspondence on thermodynamics between Douglas Robert Wilkie and Anthony C. Legon1973-1974
DRW/2/1/8Correspondence on thermodynamics between Douglas Robert Wilkie and Ilya Prigogine1970-1973
DRW/1/1/101Research file on Thermodynamics, compiled by Douglas Robert Wilkie1972-1987
DRW/2/2/2General scientific and professional correspondence file of Douglas Robert Wilkie for the years 1950-19551950-1955
DRW/2/2/14General scientific and professional correspondence file of Douglas Robert Wilkie for the years 1975-19781975-1978
DRW/2/2/21Scientific correspondence between Douglas Robert Wilkie and Mildred Cohn1977
DRW/2/2/20Scientific correspondence between Douglas Robert Wilkie and Halvor Niels Christensen1974
DRW/2/2/22Scientific correspondence between Douglas Robert Wilkie and Arpad Csapo1976
DRW/2/2/23Scientific correspondence between Douglas Robert Wilkie and Mary Joan Dawson1972-1996
DRW/2/2/24Scientific correspondence between Douglas Robert Wilkie and Maria Dydyńska1962-1969
DRW/2/2/26Scientific correspondence between Douglas Robert Wilkie and Bruno Günther & E. Guerra1959-1975
DRW/2/2/27Scientific correspondence between Douglas Robert Wilkie and Andrew Fielding Huxley1972-1976
DRW/2/2/25Scientific correspondence between Douglas Robert Wilkie and Albrecht Fleckenstein1961
DRW/2/2/28Scientific correspondence between Douglas Robert Wilkie and Brian R. Jewell1962-1981
DRW/2/2/29Scientific correspondence between Douglas Robert Wilkie and Georges Maréchal1963-1965
DRW/2/2/30Scientific correspondence between Douglas Robert Wilkie and Eric Ponder1963-1964
DRW/2/2/31Scientific correspondence between Douglas Robert Wilkie and George Porter1966-1987
DRW/2/2/32Scientific correspondence between Douglas Robert Wilkie and William Albert Hugh Rushton1941
DRW/2/2/33Scientific correspondence between Douglas Robert Wilkie and Kent Paul Sahlin1979
DRW/2/2/34Scientific correspondence between Douglas Robert Wilkie and Lawrence Stark1956-1958
DRW/2/2/35Scientific correspondence received and sent by Douglas Robert Wilkie at University College London1959-1987
DRW/2/2/36Scientific correspondence between Douglas Robert Wilkie and E. Watson Williams1959-1960
DRW/1/2/14Nuclear Magnetic Resonance talks, delivered by Douglas Robert Wilkie1975-1976
DRW/2/3/1General personal correspondence arranged by Douglas Robert Wilkie1940-1982
DRW/2/3/2Personal correspondence arranged by Douglas Robert Wilkie, with named correspondents1942-1996
DRW/2/3/3Romantic correspondence arranged by Douglas Robert Wilkie 1963-1986
DRW/2/3/5Medical correspondence arranged by Douglas Robert Wilkie1983-1998
DRW/2/3/6Farewell party letters arranged by Douglas Robert Wilkie1989
DRW/2/3/7Power of attorney letters arranged by Douglas Robert Wilkie1967-1968
DRW/2/3/8Letters of condolence on the death of Douglas Robert Wilkie1998
DRW/2/3/9Posthumous arrangements following the deaths of June Rosalind Wilkie and Douglas Robert Wilkie1995-1998
DRW/2/3/4Divorce correspondence arranged by Douglas Robert Wilkie1981-1983
DRW/3/1Douglas Robert Wilkie's personal copy of the Physician’s Handbook1941-1942
DRW/3/2Douglas Robert Wilkie's personal copy of Songs of Yale1943
DRW/3/3Appointment notebooks kept by Douglas Robert Wilkie1937-1998
DRW/3/4Passports belonging to Douglas Robert Wilkie1942-1993
DRW/3/5Examination records retained by Douglas Robert Wilkie1943-1945
DRW/3/6Notebook entitled "Scarlet Fever Notes, Dusky Ruth II", created by Douglas Robert Wilkie1978-1994
DRW/3/7Rockefeller reunion records kept by Douglas Robert Wilkie1989
DRW/3/8Leatherhead reunion records kept by Douglas Robert Wilkie1990
DRW/3/9Professional documents of Douglas Robert Wilkie1950-1983
DRW/3/10Copy of the Royal Society Obituary of Douglas Robert Wilkie2001
DRW/4Photographic and audiovisual records of Douglas Robert Wilkie1940-1999
DRW/4/1Album of photographs arranged by Douglas Robert Wilkie1938-1944
DRW/5Objects belonging to Douglas Robert Wilkiec. 1944-1980
DRW/4/2General photographs arranged by Douglas Robert Wilkie (1940s and 1950s)1940-1959
DRW/4/4General photographs arranged by Douglas Robert Wilkie (1960s and 1970s)1960s
DRW/4/3Photographs of Archibald Vivian Hill and Krista Kostial-Šimonović, retained by Douglas Robert Wilkie1952
DRW/4/5Dr Nancy Curtin photographs, retained by Douglas Robert Wilkie1970
DRW/4/6Photographs of Douglas Robert Wilkie and family, taken by Anthea Sieveking1971
DRW/4/7Farewell party to Charlie Evans photographs, retained by Douglas Robert Wilkie29 June 1978
DRW/4/8General photographs arranged by Douglas Robert Wilkie (1980s and 1990s)1980-1999
DRW/4/9Science Museum (NMR) photographs retained by Douglas Robert Wilkie1982
DRW/4/10Photographs by Kazuhiro Yamada, retained by Douglas Robert Wilkie1982
DRW/4/11Archibald Vivian Hill Centenary Symposium photograph, retained by Douglas Robert Wilkie1985
DRW/4/12Group photographs retained by Douglas Robert Wilkie1970-1999
DRW/4/13RAF Singapore and other travel photographs, retained by Douglas Robert Wilkie1942-1949
DRW/4/14Photographic slides and negatives, collected by Douglas Robert Wilkie1950-1999
DRW/4/15Glass plate negatives retained by Douglas Robert Wilkie1950-1999
DRW/4/16Audio learning tape on thermodynamics, featuring Douglas Robert Wilkie1976
DRW/1/1/102Archive floppy disks, created by Douglas Robert Wilkie1988-1991
DRW/5/1Experimental Apparatus 11940-1990
DRW/5/2Experimental Apparatus 21940-1990
DRW/5/3Forbes lecture medal and plaque, retained by Douglas Robert Wilkie1972
DRW/5/4RAF forage cap, belonging to Douglas Robert Wilkie1940-1990
DRW/5/5Astro Compass, owned by Douglas Robert Wilkie1940-1990
DRW/5/6Microscopic slides, belonging to Douglas Robert Wilkie7 October 1995
DRW/3/11House file belonging to Douglas Robert Wilkie1954-1955
DRW/6/1Scientific papers and correspondence of June Rosalind Wilkie, retained by Douglas Robert Wilkie1950-1970
DRW/6/2Personal correspondence of June Rosalind Wilkie, retained by Douglas Robert Wilkie1947-1983
DRW/6/3Personal records of June Rosalind Wilkie, retained by Douglas Robert Wilkie1935-1994
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