| RefNo | EC/1977/29 |
| Previous numbers | Cert XX, 74 |
| Level | Item |
| Title | Ramachandran, Gopalasamudram Narayana: certificate of election to the Royal Society |
| Date | 1973 |
| Description | Citation typed |
| Citation | G.N. Ramachandran has made significant contributions to the field of crystal structure analysis. These include: the technique of determining the phases of X-ray reflections from anomalous dispersion effects; and the development of novel types of Fourier synthesis for revealing the full structure from partial knowledge concerning it. Recently, he has developed a "convolution method", which is a modification of the standard Fourier technique, but faster and as accurate ad the Fourier method, which has got good prospects of application to radiographs and electron micrographs. The most significant scientific results obtained by G.N. Ramachandran have been in the field of bio-molecular structure. These include: (i) the proposed triple helical structure of collagen which is now universally accepted and is being widely applied in chemical and biological studies on collagen; (ii) development of an important technique whereby the mutual orientations of two peptide units, which are allowed, can be determined from a knowledge of the limiting contact distances to which two non-bonded atoms can approach each other; a plot of the regions of allowed and disallowed conformations is often referred to as the 'Ramachandran map'; (iii) application of the latter for examining the allowed and disallowed regions of the conformations of side groups of proteins, of linked nucleotides, and of polysaccharide chains, energy minimisation of the collagen triple helix and conformation of anti-biotics. He is now working on the application of NMR to the determination of peptide structure. |
| AccessStatus | Closed |
Fellows associated with this archive
| Code | PersonName | Dates |
| NA4682 | Ramachandran; Gopalasamudram Narayana (1922 - 2001) | 1922 - 2001 |