RefNo | EC/1995/02 |
Level | Item |
Title | Campbell, Iain Donald: certificate of election to the Royal Society |
Date | 19917/07/ |
Description | Citation typed |
Citation | Distinguished for his contributions to the study of important giological problems and particularly to the determination of protein structures in solution using nuclear magnetic resonance. Since 1971 he has played a major part in the development of new NMR instrumentation and techniques. Through hsi role in the Oxford Enzyme Group NMR facility which included the first superconducting Fourier transform syustem, he contributed to the dominance of Oxford in biological applications of NMR in the early '70s, both in technique development and structural and functional studies of enzymes, He recognised that NMR is uniquely suited for the non-invasive investigation of cellular systems and degeloped spin-echo and 1H editing techniques to studey metabolites, isotope exchange, trnasport and enzyme activities in situ. Many of these techniques and the concepts he started are now widely used by others. In 1986 he solved the solution structure of epidermal growth factor. By combining protein expresssion techiques with NMR, he developed a "dissect and re-build" strategy for studying the structure of large proteins made up from modules. The approach resulted in the determination of several new and important module structures applicable to proteins found in complement, extracellular matric and |
AccessStatus | Closed |
Fellows associated with this archive
Code | PersonName | Dates |
NA4237 | Campbell; Iain Donald (1941 - 2014) | 1941 - 2014 |