RefNo | EC/1999/03 |
Level | Item |
Title | Beddington, Rosa Susan Penelope: certificate of election to the Royal Society |
Date | 1998 |
Description | Citation typed |
Citation | Beddington's work has combined classical embryology with molecular genetics. She has established using her great skills in micromanipulation, many of the key features of gastrulation in the mouse, a fundamental process in mammalian development. She was the first to demonstrate the axis-inducing activity of the mouse node and to show that the epiblast gives rise to all the adult organs. Most recently she has identified two homeobox genes involved in the specification of anterior structures, including the forebrain. This work provides the first evidence that axial pattern in mammalian development originates in extra-embryonic tissue and that anterior identity is established before the formation of the primitive streak. It provides new insights into antero-posterior patterning throughout the vertebrates. |
AccessStatus | Closed |
Fellows associated with this archive
Code | PersonName | Dates |
NA1551 | Beddington; Rosa Susan Penelope (1956 - 2001); developmental biologist | 1956 - 2001 |