Record

Authorised form of name	Reich; Edward (1927 - 2018)
Dates	1927 - 2018
Nationality	Canadian
Date of birth	03/04/1927
Date of death	26/09/2018
Occupation	Biochemist
Membership category	Fellow
Date of election	19/03/1981
Age at election	53
OtherInfo	Edward Reich was known for his work on antibiotics that interact with nucleic acids and their related enzyme systems. He established that mitomycin C leads to loss of cellular nucleic acid and showed that actinomycines inhibit DNA-directed RNA synthesis, with selective interaction with deoxyguanosine residues and proposed a selective binding onto the exterior of helical DNA. He also established the properties of nucleotide analogues such as tubercidin and formycin. Edward developed the observation that tumour cells release fibrinolytic activity with a thorough study of both the release of plasminogen activators from cells and the relationship of this fibrinolytic activity to such fundamental matters as cell migration and inflammation, neoplasia, viral cell transformation, the release of the ovum at ovulation, trophoblast implantation and embryonic modelling. He purified nicotinic receptors and carried out extensive studies of the binding of drugs to them.
Virtual International Authority File	http://viaf.org/viaf/40876682
Code	NA3964

Archives associated with this Fellow

RefNo	Title	Date
EC/1981/37	Reich, Edward: certificate of election to the Royal Society	1979

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