Citation | Distinguished for his work on the movement of ions through cell membranes and on the relation of active transport to phosphorus metabolism. He obtained quantitative information about the linkage of K uptake and Na outflow in red cells, and showed that the membrane ATPase is activated by external K and internal Na. He has made illuminating studies on the action of cardiac glycosides on ion transport and on the detailed mechanism by which the breakdown of ATP leads to an uphill movement of ions. Glynn has also obtained evidence that the pumping mechanism is reversible, by showing that a downhill movement of ions may lead to the formation of ATP. |