| RefNo | EC/1973/02 |
| Previous numbers | Cert XIX, 76 |
| Level | Item |
| Title | Askonas, Brigitte Alice: certificate of election to the Royal Society |
| Description | Citation typed. Letter attached to certificate. |
| Citation | Distinguished for her studies on the mechanism of the synthesis of immunoglobulins and on the immunological function of antigens in macrophages. After her earlier work on the synthesis of antibodies by tissues in vitro. Dr. Askonas turned her attention to myeloma proteins made by transplantable plasma cell tumours of mice, which she recognized as one of the few available sources of immunoglobulin sufficiently homogeneous to allow the application of exact methods of analysis. By an elegant combination of immunochemical and biochemical methods she and A.R. Williamson have provided new insight into the way in which the light and heavy chains of myeloma immunoglobulins are synthesized and assembled within the cell, and have shown that their findings apply to lymph node cells forming antibody. She has also made important investigations of the fate of antigens within macrophages and of their immunogenic activity. |
| AccessStatus | Open |
Fellows associated with this archive
| Code | PersonName | Dates |
| NA5318 | Askonas; Brigitte Alice (1923 - 2013); immunologist and biochemist | 1923 - 2013 |