| RefNo | EC/1974/06 |
| Previous numbers | Cert XIX, 117 |
| Level | Item |
| Title | Curtis, David Roderick: certificate of election to the Royal Society |
| Description | Citation typed |
| Citation | The candidate's work is concerned with the development and use of microtechniques for an analysis of the chemical sensitivity of single nerve cells in the mammalian central nervous system, as a means of identifying synaptic transmitter substances. These "micro-electrophoretic" techniques with multibarrel micropipettes provide a method for comparing synaptic responses with those produced by the administration of known substances into the external environment of a neurone, and have become of major significance in investigations of the pharmacology of the brain and spinal cord. He has studied particularly the action of acetylcholine and amino acids at the cellular and membrane level. He was first to demonstrate the central excitant actions of glutamic, aspartic and related acidic amino acids. His most recent and important research centres on the function of glycine as the transmitter at strychnine-sensitive inhibitory synapses. |
| AccessStatus | Closed |
Fellows associated with this archive
| Code | PersonName | Dates |
| NA4375 | Curtis; David Roderick (1927 - 2017) | 1927 - 2017 |