| RefNo | EC/1999/18 |
| Level | Item |
| Title | Grigg, Ronald Ernest: certificate of election to the Royal Society |
| Date | 1997 |
| Description | Citation typed on separate piece of paper, then pasted onto certificate |
| Citation | Distinguished for his contributions to the design and development of cascade processes (ie multireaction 'one-pot' sequences), based on palladium-catalysed cyclisation reactions and 1,3-dipolar cycloadditions, and their applications in general organic synthesis. Early work made notable contributions to the synthesis and fundamental chemistry of natural porphyrins and polypyrrole macrocycles; some of this work has recently been developed by others for sensor systems. A major contribution has been to research the cascade processes involving amine - imine - azomethine ylide - cycoadduct, and oxime - nitrone - cycloadduct. Chiral versions of imine based 1,3-dipolar cycloadditions developed by Grigg are now widely exploited by industry especially in the area of combinatorial chemistry, and his invention of a new reagent for the detection of latent fingerprints, based on early azomethine ylide studies, won a UK government SMART award in 1989. Grigg's group is one of the best in the world researching the area of palladium chemistry. Thus, he described the first homochiral Heck reaction, invented the concept of palladium-catalysed cyclisation-anion capture methodology and was one of the pioneers developing palladium-catalysed cascade ring forming reactions, more recently in tandem with a range of novel cycloaddition processes. In particular, his original innovative contributions in the areas of 1,3-diplor cycloaddition reactions and palladium-catalysed cascade processes have made him widely regarded as one of the leading organic chemists in the field. |
| AccessStatus | Closed |
Fellows associated with this archive
| Code | PersonName | Dates |
| NA2351 | Grigg; Ronald Ernest (1935 - 2021) | 1935 - 2021 |