| Citation | Hartmut Michel is distinguished for pioneering the crystallisation of membrane proteins and for structure determination of assemblies of bioenergetic membrane proteins. He introduced methods for crystallising membrane proteins using amphiphiles and monoclonal antibodies, recently used by others to crystallise ion channels and transporters. His work led to the structures of bacterial photosynthetic reaction centres, the first membrane protein to be determined, and of bacterial cytochrome c oxidase, used by Michel as a basis for detailed mechanistic studies. He received the Nobel Prize in Chemistry in 1988 (with R Huber and J Deisenhofer). |