Citation | Martin Chalfie is celebrated for developing Green Fluorescent Protein as a universal biomarker, for which he shared the Nobel Prize in Chemistry for 2008, but that achievement forms only part of his extensive contributions to cell and developmental biology, neurobiology and methodology. Most of these have come from his 40-year-long studies of mechanosensory neurons in the nematode C. elegans, which have generated many major discoveries in neuronal specification and differentiation, neurodegeneration, microtubule structure and function, mechanosensory transduction and its modulation, connectomics, neuronal outgrowth, and currently determinants of neuronal circuitry, neuronal ensheathment and developmental robustness. He remains extraordinarily productive and creative. |