| RefNo | EC/2020/21 |
| Level | Item |
| Title | Lu, Xin: certificate of election to the Royal Society |
| Date | 14 April 2020 |
| Description | Certificate endorsing election of Xin Lu as a Fellow of the Royal Society. Includes personal details of the elected Fellow, citaion giving the reasons for election, and names of proposers. Signed by the Executive Director of the Royal Society, Julie Maxton. |
| Citation | Xin Lu has provided fundamental insights into cancer biology including the seminal discovery of the first protein family - the ASPPs - that regulates the target selectivity of tumour suppressor p53. This discovery revealed new pathways to induce selective killing of cancer cells, and led her to discover a new general nuclear import pathway and show how protein co-factors can regulate transcription factor target selection. She established that the ASPPs influence cancer initiation and can underlie brain abnormalities and sudden cardiac death. She was also among the first to identify how p53 responds to oncogene activation and DNA damage signals. |
| Extent | 4p |
| Format | Computer printout |
| PhysicalDescription | A4 papers |
| AccessStatus | Closed |
| AccessConditions | Election certificates are subject to 50 year closure period from date of election. Details of proposers are kept confidential until the 50 year closure period has elapsed. |