| Authorised form of name | McLaren; Dame; Anne Laura Dorinthea (1927 - 2007); geneticist |
| Dates | 1927 - 2007 |
| Nationality | British |
| Place of birth | 38 South Street, Mayfair, London, England |
| Date of birth | 26 April 1927 |
| Place of death | North Weald Bassett, Essex, England |
| Date of death | 07 July 2007 |
| Occupation | Geneticist |
| Research field | Genetics |
| Reproductive biology |
| Activity | Education:
BSc in zoology (Oxford); MA (1949); doctorate, Oxford (1952)
Career:
Joined the Institute of Animal Genetics at the University of Edinburgh, studying fertility, development and epigenetics, as well as the development of mouse embryonic transfer, immunocontraception, and the skeletal characteristics of chimerae(1959-1974); Director of the Medical Research Council, London (1974-1992); Principal Research Associate Wellcome/Cancer Research Campaign Institute, Cambridge (1992-2007); died in a car crash on the M11 motorway while travelling back from Cambridge to London.
Honours:
DBE 1993
Awards/Medals:
scientific medal of the Zoological Society of London (1967)
Marshall medal of the Society for the Study of Fertility (1985)
European Woman Scientist of the Year (2001)
Japan prize of the Science and Technology Foundation of Japan (2002)
March of Dimes prize in developmental biology (2007)
Memberships:
FRCOG
British Association for the Advancement of Science
Academy of Medical Sciences |
| Membership category | Fellow |
| Date of election | 20/03/1975 |
| Age at election | 47 |
| RSActivity | Royal Society roles:
Council: 1985-1987, 1991-1996; For Sec 1991-1996 (first female Foreign Secretary); VP
Medals and prizes:
Royal Medal 1990 |
| Relationships | Parents: Henry Duncan McLaren, second Baron Aberconway (1879–1953), politician and industrialist, and Christabel Mary Melville, née Macnaghten (1890–1974).
Spouse: Dr Donald Michie (m. 1952), divorced 1959.
Children: One son and two daughters. |
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| OtherInfo | Distinguished for her researches on reproductive physiology, particularly of the mouse. By applying a wide range of techniques to single species, she has contributed significantly to many subjects of fundamental importance, e.g. egg transfer, hormonal control of ovulation, effects of superovulation on subsequent pregnancy, placental and foetal growth, interactions between embryo and uterus during implantation, relation between immunology and fertility, effects of maternal and foetal genotype on prenatal development etc.
Identified the earliest primordial germ cells through alkaline phosphatase staining and explored the role of testes cord formation and meiosis blockage in male genital ridges.
Remembered for her participation in setting up the Stem Cell Centre and the Centre for Trophoblast Research at Cambridge University.
Her papers can be found in the British Library collections.
She sought to promote the attractions of a scientific career for women, founding the Association of Women in Science and Engineering (AWiSE).
At the age of 7 she appeared in the film version of H. G. Wells' novel Things to Come, released in 1936. |
| Royal Society Obituary or Memoir | Click to view (may be contained within a meeting notice, presidential address or list of death notices) |
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| Source | DNB
Biographical Memoirs of the Fellows of the Royal Society, Ann Clarke and Martin H. Johnson FRS, 01 March 2023, Royal Society Publishing, on the Royal Society website [URL: https://doi.org/10.1098/rsbm.2022.0053; last accessed: 22/01/2025] |
| Virtual International Authority File | http://viaf.org/viaf/22201744 |
| Code | NA1981 |