Authorised form of name | Sambrook; Joseph Frank (1939 - 2019) |
Dates | 1939 - 2019 |
Nationality | British |
Place of birth | Liverpool, Merseyside, England, United Kingdom |
Date of birth | 01/03/1939 |
Date of death | 14/06/2019 |
Occupation | Molecular biologist |
Research field | Biochemical genetics |
Molecular virology |
Cancer cells |
Activity | Education: University of Liverpool BSc hons (1962); Australian National University, PhD (1966) Career: Postdoctoral researcher, Medical Research Council Laboratory of Molecular Biology (1966 -1967), postdoctoral researcher Salk Institute for Biological Studies (1967-1969) ; Cold Spring Harbor Laboratory (1969); University of Texas Southwestern Medical Centre Dallas; Peter MacCallum Cancer Centre (1995); Executive Scientific Director of the Stem Cell Centre Monash University; founding Director of kConFaB, Australia's National Consortium for Research into Familial Breast Cancer Memberships: FAA
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Membership category | Fellow |
Date of election | 21/03/1985 |
Age at election | 46 |
Relationships | Hired to work at Cold Spring Harbor Laboratory by James Watson FRS |
OtherInfo | Joseph Sambrook made many important contributions to molecular and biochemical genetics, studying animal viruses, and particularly those viruses with DNA that integrate into the host cell genome. He was a member of the group that first demonstrated the physical integration of the DNA sequences of SV40 and other polyoma viruses into the chromosomes of the cells they transform. He subsequently defined the sequences which are necessary and sufficient to effect malignant transformation, and was a pioneer in the use of restriction enzymes for the physical mapping of mutations in adenovirus. He was the first to analyse the DNA sequences of the integration sites of SV40, work that confirmed the ‘onion skin’ model of excision. Joseph also analysed the expression of influenza virus haemagglutinin from genes cloned in SV40 vectors and studied the factors influencing the transport of haemagglutinin to the cell surface by in vitro modification of the genes. |
Source | Sources: https://web.archive.org/web/20120317114007/http://www.thankyouday.org/ThankYouDayAwards/ThankYouDayAwards2009.aspx Reference: https://en.wikipedia.org/wiki/Joseph_Sambrook |
Virtual International Authority File | http://viaf.org/viaf/41900839 |
Code | NA4781 |
Archives associated with this Fellow
RefNo | Title | Date |
EC/1985/34 | Sambrook, Joseph Frank: certificate of election to the Royal Society | 1984 |