Record

Reference numberEC/1994/11
LevelItem
TitleDavies, Julian Edmund: certificate of election to the Royal Society
Date31/07/1987
DescriptionCitation typed
Citation Julian Davies began his biological work studying the mode of action of antibiotics in relation to the structure and function of ribosomes. He showed that streptomycin induced translation errors by a misreading of the code. He continued to work on the structure and function of bacterial ribosomes and was able to characterize mutants in several ribosome genes and, through an analysis of sensitivity and resistance to the antibiotic kasugamycin, isolated the first mutants which affected the post-transcriptional modification of ribosomal RNA. His main work has been on the biochemical mechanisms of resistance to antibodies in clinical isolates of bacteria harboring resistance plasmids. He demonstrated the specificity of O-phosphorylation, O-adenylylation and N-acetylation of aminoglycoside antibiotics and was the first to suggest that resistance genes originally came from the producing organisms and spread by horizontal gene transfer. This has been borne out by research on drug-resistance elements.
Access statusClosed
Add to My Items

    Collection highlights

    Browse the records of some of our collections, which cover all branches of science and date from the 12th century onwards. These include the published works of Fellows of the Royal Society, personal papers of eminent scientists, letters and manuscripts sent to the Society or presented at meetings, and administrative records documenting the Society's activities since our foundation in 1660.

    The Royal Society

    The Royal Society is a Fellowship of many of
    the world's most eminent scientists and is the
    oldest scientific academy in continuous existence.
    Registered charity number 207043

    Website design ©CalmView



    CONTACT US

    + 44 207 451 2500
    (Lines open Mon-Fri, 9:00-17:00. Excludes bank holidays)

    6-9 Carlton House Terrace, London SW1Y 5AG

    Email Us →

    SUBSCRIBE

    Subscribe to our newsletters to be updated with the
    latest news on innovation, events, articles and reports.

    Subscribe →

    © CalmView