| RefNo | EC/1975/11 |
| Previous numbers | Cert XIX, 159 |
| Level | Item |
| Title | Dalziel, Keith: certificate of election to the Royal Society |
| Description | Citation typed |
| Citation | Distinguished for his studies of the kinetics and mechanism of enzyme catalysed reactions. His exacting studies of liver alcohol dehydrogenase and his development of theoretical treatments of the precise data obtained set new standards in the field. Observations such as the unusual lack of stereo specificity of this enzyme towards optically active substrates led to considerable clarification of the mechanism of action. These soundly based methods have been applied to dehydrogenases catalysing more complex coupled reactions involving three substrates and the kinetic theory developed to include these systems and also allosteric enzymes. Oxidative decarboxylases have been shown by a simple elegant technique to use dissolved carbon dioxide rather than carbonic acid or bicarbonate ion as substrate for the reverse carboxylation reaction. The systematic and rigorous development of theory based on detailed and accurate quantitative data with a progression from relatively simple to more complex systems have established Dalziel's reputation in a field which together with structural studies, is making an essential contribution to the elucidation of the mechanism of enzyme catalysis. |
| AccessStatus | Closed |
Fellows associated with this archive
| Code | PersonName | Dates |
| NA2102 | Dalziel; Keith (1921 - 1994) | 1921 - 1994 |