| RefNo | EC/1976/16 |
| Previous numbers | Cert XX, 16; A02717 |
| Level | Item |
| Title | Gibson, Frank William Ernest: certificate of election to the Royal Society |
| Date | 1974 |
| Description | Citation typed |
| Citation | Distinguished for his contributions to the biochemistry and genetics of aromatic biosynthesis leading to an understanding of the functions of ubiquinone, menaquinone and enterochelin. Gibson has elucidated the pathways, identified the intermediates, and studied the structure and functions of key enzymes in the biosynthesis of aromatic components. Major discoveries have been the identification of chorismate as the branch point in aromatic biosynthesis, and elucidation of the pathways form chorismate to ubiquinone, menaquinone and 2,3-dihydroxybenzoare. He has shown that menaquinone mediated a step in pyrimidine synthesis while ubiquinone functions in the electron transport system; this work has opened up a new approach to the study of oxidative phosphorylation and membrane function. 2,3-Dihydroxybenzoate has been shown to be a precursor of enterochelin which Gibson has identified as a carrier in iron-transport; the conformational and enzymic changes accompanying enterochelin function have been described in detail. |
| AccessStatus | Closed |
Fellows associated with this archive
| Code | PersonName | Dates |
| NA4416 | Gibson; Frank William Ernest (1923 - 2008) | 1923 - 2008 |