| RefNo | EC/1981/37 |
| Previous numbers | Cert XXI, 37 |
| Level | Item |
| Title | Reich, Edward: certificate of election to the Royal Society |
| Date | 1979 |
| Description | Citation typed |
| Citation | Distinguished for his work on antibiotics that interact with nucleic acids and their related enzyme systems. Established that mitomycin C leads to loss of cellular nucleic acid. Showed that actinomycins inhibit DNA directed RNA synthesis, with selective interaction with deoxyguanosine residues and proposed a selective binding onto the exterior of helical DNA. Established the properties of nucleotide analogues such as tubercidin and formycin. Reich has developed the observation (of Fischer) that tumour cells release fibrinolytic activity with a thorough study of the release of plasminogen activators from cells and the relationship of this fibrinolytic activity to such fundamental matters as cell migration and inflammation, neoplasia, viral cell tranformation, the release of the ovum at ovulation, trophoblast implantation and embryonic modelling. He has purified nicotinic receptors and carried out extensive studies of the binding of drugs to them. |
| AccessStatus | Closed |
Fellows associated with this archive
| Code | PersonName | Dates |
| NA3964 | Reich; Edward (1927 - 2018) | 1927 - 2018 |