| RefNo | EC/1984/20 |
| Previous numbers | Cert XXI, 156 |
| Level | Item |
| Title | Lowe, Gordon: certificate of election to the Royal Society |
| Date | 1981 |
| Description | Citation typed |
| Citation | Dr. Lowe is distinguished for contributions to an unusually wide field of organic chemistry, from natural product studies on polyacetylenes in fungi to mechanistic studies of enzyme catalysis. Early studies on the total synthesis of cephalosporin antibiotics led to syntheses of nuclear analogues of cephalosporins, which became of considerable importance in the subsequent structural elucidation of thienamycin by a group in the U.S. Researches on enzymic catalysis began with the chemistry and role of functional groups in the cystein proteinases, e.g. papain, ficin and bromelain. A brilliant synthesis of chiral 16O, 17O, 18O-methyl phosphate led to extensive and fruitful studies on the stereochemistry of phosphoryl transfer in pyruvate kinase, creatinase kinase and yeast hexokinase. Results to date suggest this technique is to become a landmark in enzymatic studies of phosphate transfer. |
| AccessStatus | Closed |
Fellows associated with this archive
| Code | PersonName | Dates |
| NA3910 | Lowe; Gordon (1933 - 2003) | 1933 - 2003 |