| RefNo | EC/1985/22 |
| Previous numbers | Cert XXI, 204 |
| Level | Item |
| Title | Hughes-Jones, Nevin Campbell: certificate of election to the Royal Society |
| Date | 1983 |
| Description | Citation typed |
| Citation | N.C. Hughes-Jones is distinguished for his studies of the kinetics of antigen-antibody reactions, applied to red cells. He was the first to devise a method for quantitating red cell antibodies in absolute terms (microg/ml) - a development which was of considerable importance, since it made it possible to discover the minimum dose of anti-Rh needed for the suppression of Rh immunization and thereby greatly facilitated the extension of anti-Rh treatment to all women at risk of immunization following pregnancy.
Hughes-Jones has also made important quantitative studies of the activation of the classical complement pathway. He has shown that the binding of C1q is not necessarily accompanied by C1 activation and has gone on to identify the conditions of C1 binding that do result in C1 activation, thus making a real contribution to understanding of the way in which antigen-antibody reactions lead to complement activation. |
| AccessStatus | Closed |
Fellows associated with this archive
| Code | PersonName | Dates |
| NA5382 | Hughes-Jones; Nevin Campbell (1923 - 2022) | 1923 - 2022 |