| Citation | Dr. Hill was known in the early part of his career for his work with R.J.P. Williams on the chemistry of vitamin B12 and on model metal complexes designed to mimic reactive centres of metalloenzymes. This work generated much inorganic biochemistry of considerable interest. Later he studied biological reactions of oxygen, demonstrating new spin-trapping methods for free radical products. His most outstanding and recent contributions have been in the field of electron-transfer proteins where he was the first to show how to couple electrodes directly to enzyme reactions. This work is the basis of an increasing understanding of reactions of metal proteins on surfaces and has led to the development of bio-sensors of different kinds e.g. the glucose electrode. The work has been taken up in a large number of laboratories all over the world. |