| Citation | Distinguished for his contributions to our understanding of the cell and molecular biology of eukaryotic microbes, especially fungi, slime molds and trypanosomes. His work has provided important insights into how cells construct their cytoskeletons by modulating tubulin gene expression and protein modification. His novel approaches have led to discovery of unusual mechanisms of microtubule initiation and the partitioning of genomes in sleeping sickness trypanosomes, also of the relationship of division to differentiation in these parasites. His discovery of the mode of action of the antifungal agent griseofulvin has been followed by explanations of the selective toxicity and resistance mechanisms of fungicides and anthelminthics. |