Record

RefNoEC/2006/13
LevelItem
TitleFeldmann, Marc: certificate of election to the Royal Society
DescriptionCertificate of Election
CitationAutoimmune diseases are common chronic disabling illnesses with no effective therapy until recently. In elegant studies in vitro, Feldmann demonstrated that antibodies to tumour necrosis factor (TNF) blocked the production of major pro-inflammatory cytokines in joint synovium of rheumatoid arthritis (RA) patients.
Furthermore, blocking TNF in animal models of RA ameliorated disease. Feldmann, together with his clinical colleagues, then treated RA patients with anti-TNF monoclonal antibodies with spectacular results, especially with methotrexate. A million patients have now been treated, with profound impact on medical practice. Furthermore this seminal conceptual advance has been applicable to a variety of other diseases.
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    Browse the records of some of our collections, which cover all branches of science and date from the 12th century onwards. These include the published works of Fellows of the Royal Society, personal papers of eminent scientists, letters and manuscripts sent to the Society or presented at meetings, and administrative records documenting the Society's activities since our foundation in 1660.

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