Record

RefNoEC/2006/15
LevelItem
TitleFreeman, Matthew John Aylmer: certificate of election to the Royal Society
DescriptionCertificate of Election
CitationMatthew Freeman has studied the regulation of intercellular signalling, mainly in Drosophila. He showed, in the eye, that repeated signalling through the epidermal growth factor receptor (EGFR) is used to determine all retinal cell fates; this model has become a paradigm for induction by receptor tyrosine kinases. Dissecting and studying the molecular components of EGFR signalling, he showed how the receptor can establish pattern, for example through feedback regulation. His discoveries include the signalling inhibitors Argos and Sprouty, and he has shown that rhomboids are a novel family of intramembrane proteases that are conserved throughout evolution.
AccessStatusClosed
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    Browse the records of some of our collections, which cover all branches of science and date from the 12th century onwards. These include the published works of Fellows of the Royal Society, personal papers of eminent scientists, letters and manuscripts sent to the Society or presented at meetings, and administrative records documenting the Society's activities since our foundation in 1660.

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