Citation | Steve Jackson has contributed to several fields of research. he was instrumental in elucidating the NHEJ pathway of DNA double-strand break repair, being the first to: identify a mammalian NHEJ factor; provide insights into how NHEJ factors function; and show that in addition to repairing radiation damage, these proteins function in telomere maintenance and help to generate the vertebrate immune system. In the transcription field, Professor Jackson established that many transcription factors are glycosylated, that RNA polymerase III transcription requires TATA-box binding protein and, through his work on Archaea, he has provided fundamental insights into transcriptional control mechanisms. |