Description | David Glover is principally known for his work on the control of the cell cycle in Drosophila. Amongst the many genes discovered by his lab are those encoding the Polo and Aurora protein kinases that are required for progression through mitosis. Glover has documented the multiple roles played by these enzymes in mitosis and cytokinesis and has helped to develop small molecule inhibitors that may prove useful for cancer therapy, since these proteins are overexpressed in certain tumours. As a postdoctoral fellow in Stasnford, Glover was one of the pioneers of cloning eukaryotic DNA in bacterial vectors, and discovered the pressence of introns in the ribosomal RNA genes of Drosophila. |