| Description | Dr Hemmings has made major contributions to our understanding of the molecular basis of protein phosphorylation-dependent signal transduction. He was the first to identify the protein kinase PKB and has maintained a pioneering role in defining the crucial role of this enzyme in the regulation of signalling pathways by insulin and growth factors in health and disease. These efforts have been complemented by seminal work on the protein phosphatases, including definition of the molecular and functional complexities of protein phosphatase 2A. The importance of his work is reinforced by his ranking of 62 out of the 100 top cited scientists in the world in the Biology and Biochemistry section of ISI
( http://www.in-cites.com/nobel/2005-bio-top100.html ) |