Citation | Gillian Griffiths has made key contributions to the fields of both cell biology and immunology, introducing important new concepts into both fields. Gillian Grififiths was one of the first to show that immune cells used specialised mechanisms of secretion, identifying the proteins and mechanisms controlling secretion from cytotoxic T lymphocytes by studying human genetic diseases and biochemical approaches. Her work has identified a new and unexpected role for the centrosome in exocytosis, and revealed that centrosome docking at the plasma membrane provides a focal point for exocytosis and endocytosis. Her work is both elegant and insightful. |