Citation | Professor Gero Miesenböck, Waynflete Professor of Physiology and Director of the Centre for Neural Circuits and Behaviour, University of Oxford
Gero Miesenboeck pioneered the science of optogenetics. He established the principles of optogenetic control in 2002, using rhodopsin to activate normally light-insensitive neurons. He was the first to use optogenetics to control behaviour. These seminal experiments have provided a platform for an explosion in optogenetic applications. Recent honours testify to the significance of these findings. Miesenboeck has exploited optogenetics in a succession of brilliant experiments illuminating synaptic connectivity, the neural basis of reward, mechanisms of sleep homeostasis and the control of sexually dimorphic circuitry. These incisive contributions to neuroscience have demonstrated the full potential of optogenetics beyond the proof-of-principle stage.
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