RefNo | EC/2021/31 |
Level | Item |
Title | Platt, Frances Mary: certificate of election to the Royal Society |
Date | 21 April 2021 |
Description | Certificate endorsing election of Frances Platt as a Fellow of the Royal Society. Includes personal details of the elected Fellow, citation giving the reasons for election, and names of proposers. Signed by the Executive Director of the Royal Society, Julie Maxton. |
Citation | Frances Platt is an expert on glycosphingolipids (GSL) and glycosphingolipid (GSL) lysosomal storage disorders. She pioneered the first pharmacological approach for treating these disorders that she termed substrate reduction therapy (SRT). This led to the development of an approved drug (miglustat) for type 1 Gaucher disease which was the first oral therapy for a lysosomal storage disorder. Miglustat was subsequently approved as the first-disease-modifying therapy for a progressive neurodegenerative lysosomal storage disorder, Niemann-Pick disease type C. A second drug she pioneered (lucerastat) is currently in Phase 3 clinical trials for the lysosomal storage disorder Fabry disease.Frances Platt is an expert on glycosphingolipids (GSL) and glycosphingolipid (GSL) lysosomal storage disorders. She pioneered the first pharmacological approach for treating these disorders that she termed substrate reduction therapy (SRT). This led to the development of an approved drug (miglustat) for type 1 Gaucher disease which was the first oral therapy for a lysosomal storage disorder. Miglustat was subsequently approved as the first-disease-modifying therapy for a progressive neurodegenerative lysosomal storage disorder, Niemann-Pick disease type C. A second drug she pioneered (lucerastat) is currently in Phase 3 clinical trials for the lysosomal storage disorder Fabry disease. |
Extent | 4p |
Format | Computer printout |
PhysicalDescription | A4 papers |
AccessStatus | Closed |
AccessConditions | Election certificates are subject to 50 year closure period from date of election. Details of proposers and date certificate was first submitted for candidacy are kept confidential until the 50 year closure period has elapsed. |